Scientist Preclinical Immunogenicity-II

Dr. Reddy’s Laboratories Ltd. is a leading multinational pharmaceutical company based across global locations. Each of our 24,000 plus employees comes to work every day for one collective purpose: to accelerate access to affordable and innovative medicines because Good Health Can’t Wait.
We started in 1984 with a modest investment, 20 employees and a bold vision. Today, we have research and development centres, manufacturing facilities or a commercial presence in 66 countries. 
For nearly four decades, we have stood for access, affordability and innovation based on the bedrock of deep science, progressive people practices and robust corporate governance. As the pharmaceutical industry evolves and undergoes disruption, we see an opportunity – to strengthen our core further (the next steps) and to build the future (the new bets).
‘The Next and the New’ is how we aim to continue to be the partner of choice – purpose-driven, future-ready and sustainable.  Our aim is to reach over 1.5 Bn+ patients across the world by 2030 by growing our core businesses and building for the future with sustainability at the core of our purpose and strategy. Sustainability for us means operating in a manner that respects people, planet and purpose – helping us conserve precious resources, serve our patients, create value for stakeholders, give back to society, fulfil our potential and maintain our integrity and transparency
Dr Reddy’s maintains a work environment, free from discrimination and is an equal opportunity employer. We are committed to employ & nurture all qualified diverse workforce without regard to race, colour religion, nationality, sex, age, disability status, genetics, sexual orientation, gender expression, citizenship or any other characteristic or classification protected by applicable law(s) of the country we operate in. We treasure every talent, and recognize merit and diversity in our organization.

Job Summary

We are seeking a skilled, enthusiastic, and experienced Scientist to join our Immunogenicity team. This role focuses on supporting Immunogenicity Risk Assessment for complex generics and differentiated products, spanning strategy, development, and product approval across diverse therapeutic areas and global markets.

Roles & Responsibilities

·  Immunogenicity Risk Assessment

• Develop and implement strategies for in-vitro immunogenicity risk assessments.
• Conduct literature reviews, execute experiments, and evaluate product risks during development and regulatory submission stages.

·  Assay development and execution

• Independently design, optimize, and perform in-vitro assays, including flow cytometry-based immune cell profiling, cell-based assays, immunological assays, and biomarker analysis.
• Work with human PBMCs and established mammalian cell cultures.

·  Cytokine and T-cell Assays

• Establish and validate cytokine release assays using multiplexing/ELISA techniques.
• Perform immune cell viability and T-cell proliferation assays with PBMCs using flow cytometry.

·  Study Co-ordination and Data analysis

• Plan, execute, and coordinate nonclinical in-vitro studies.
• Manage samples in collaboration with cross-functional teams.
• Conduct experiments, analyze data, perform statistical evaluations, and compile reports for internal review.

·  Documentation and Compliance

• Prepare and maintain SOPs, STPs, study reports, and incident records.
• Ensure strict adherence to QMS and organizational safety standards.

·  Cross-functional Collaboration

• Collaborate with internal teams and external stakeholders to support immunogenicity assessments.
• Ensure alignment with project objectives and regulatory requirements.

Educational qualification: 

• M.Tech / M.Sc in Biotechnology, Biochemistry, or Life Sciences
• M.Pharm in Pharmaceutical Sciences
• PhD in Life Sciences (Biotechnology, Immunology, Biochemistry, or related fields)

Experience Requirement

• 3-4 years of relevant experience in the pharmaceutical industry with an M.Sc/M.Tech/M.Pharm degree
• Fresh PhD graduates in Life Sciences are also eligible

Technical Skills:

• Flow Cytometry (FACS):
  • Mandatory expertise in immune cell phenotyping, multi-color panel design, fluorescence-based sorting, and data analysis.
  • Strong experience in using PBMCs and mammalian cell cultures for immunogenicity assays.
• Cell Culture & Harvesting:
  • Proficiency in maintaining and handling primary and established cell lines.
  • Skilled in sterile techniques and PBMC isolation.
• Assay Development and validation:
  • Expertise in developing and validating the in-vitro cell-based and flowcytometry based assays including ELISAs, T-cell proliferation, Dendritic and T-cell activation assays.
• Data Analysis & Reporting:
  • Skilled in statistical analysis and visualization tools (e.g., GraphPad Prism, Excel).
  • Experience in compiling study reports, SOPs, and regulatory documentation.

Behavioral Skills 

• Excellent communication and interpersonal skills.
• Strong analytical and problem-solving abilities.
• Ability to work collaboratively with own team and cross-functional teams. 
• Ability to multi-task, prioritize and deliver effectively under stringent timelines

About the Department
Integrated Product Development Organisation                                         

We integrate our deep science capabilities and cutting-edge technology to develop innovative, accessible and affordable therapies for patients worldwide. We are a science-driven, innovation-focused pharmaceutical company committed to accelerating access to healthcare solutions to patients around the world. We have End to end capabilities in API, Formulations, Clinical, Intellectual Property and Regulatory Affairs. We are serving 55+ markets including USA, Canada, Europe, China, LATAM, ASEAN and all Emerging Markets with innovative and generic products ranging from Active pharmaceutical ingredients (API), Oral formulations, Parenteral (Injectables, Opthalmics) & Other dosages
Our product development efforts drive a portfolio of more than 1,000 products Enabled by our robust R&D team consisting of more 200 scientists and functional experts and more than 150 doctorates, we have filed 1,071 patents and also published over 1,000 papers for peer review over the years.

Benefits Offered
At Dr. Reddy’s we actively help to catalyse your career growth and professional development through personalised learning programs.
The benefits you will enjoy at Dr. Reddy’s are on par with the best industry standards. They include, among other things and other essential equipment, joining & relocation support, family support (Maternity & Paternity benefits), learning and development opportunities, medical coverage for yourself and your family, life coverage for yourself.

Our Work Culture
Ask any employee at Dr. Reddy’s why they come to work every day and they’ll say, because Good Health Can’t Wait. This is our credo as well as the guiding principle behind all our actions. We see healthcare solutions not only as scientific formulations, but as a means to help patients lead healthier lives, and we’re always attuned to the new and the next to empower people to stay fit. And to do this, we foster a culture of empathy and dynamism. People are at the core of our journey over the last few decades. They have been supported by an enabling environment that buoys individual ability while fostering teamwork and shared success. We believe that when people with diverse skills are bound together by a common purpose and value system, they can make magic.
For more details, please visit our career website at https://careers.drreddys.com/#!/